Should My Child Try Food Allergy Treatment (Oral Immunotherapy)?

Use this tool to help decide if this treatment is right for your child and family.

This Tool Was Taken and Adapted from the ACAAI

If your child has a confirmed food allergy, a treatment option called Oral Immunotherapy (OIT) may offer additional protection against severe allergic reactions. OIT slowly exposes an allergic child to very precise, gradually increasing amounts of a specific food allergen—such as eggs, milk, tree nuts, or peanuts—so their immune system becomes less likely to react after an accidental ingestion.

That means if your child accidentally eats something containing their allergen, the treatment is designed to protect them from a severe, life-threatening reaction. However, even with this treatment, your child MUST continue to avoid their target food and carry two epinephrine auto-injectors at all times.

It’s important to understand:

  • OIT is not a cure – your child will still have a food allergy and must actively avoid that food in everyday life.
  • It is not meant to allow unrestricted eating – it will not automatically enable your child to freely eat the food anytime or in any amount they wish.
  • It requires strict routine – it works only while your child is taking their specific dose on a daily basis.
  • Safety rules still apply – your child will need to continue to carry two epinephrine auto-injectors, and your family will still need to read food labels closely.
  • Side effects are possible – mild to moderate allergic symptoms can occur due to the treatment itself, especially during dose increases.

For many children with food allergies and their parents, the peace of mind and protection against accidental exposure make the daily commitment worth the effort. This tool is designed to help you prepare for a conversation with your allergist to decide if OIT is a good fit for your family.

How to use this tool:

  1. Read the general facts about food allergies and how immunotherapy works.
  2. Respond to a few simple statements based on your child’s temperament and daily routines.
  3. Bring your answers to your next clinic consultation to discuss a personalized plan.

About Food Allergies

Food allergies are incredibly common in children, with milk, eggs, peanuts, and tree nuts making up some of the most frequent triggers. Protein from these foods can be hidden in many different types of pre-packaged meals, baked goods, and restaurant dishes, making accidental exposure a constant concern. The consequences of an accidental exposure can range from mild hives to life-threatening anaphylaxis.

To prevent allergic reactions, families are taught strict avoidance: asking what ingredients are in food before eating, meticulously checking nutrition labels, and always carrying two epinephrine auto-injectors. While avoidance is highly effective, many families seek an extra layer of protection to reduce the constant anxiety of a severe reaction from an accidental bite. Whether a child is undergoing treatment or practicing strict avoidance, if an allergic reaction occurs, epinephrine should be administered immediately, and emergency services should be contacted.

About Oral Immunotherapy (OIT)

Oral Immunotherapy is a medical treatment strategy utilized by specialists to manage allergies to eggs, milk, tree nuts, and peanuts. It works by deliberately exposing the child’s immune system to a tiny, microscopic amount of the allergen every single day.

The treatment process is highly structured:

  • The Initial Build-up: The child takes an exceptionally small, carefully measured dose of the food protein in a medical setting.
  • The Daily Routine: Parents mix this precise dose of allergen powder or liquid into a safe food at home every day.
  • The Escalation Phase: Every few weeks, the child returns to the office to safely increase the daily dose under direct medical supervision.
  • The Maintenance Phase: Once the target safety dose is achieved, the child stays on that daily dose indefinitely to maintain their protection.

There are several daily rules to keep in mind. The treatment dose should always be taken with a substantial meal. Furthermore, physical activity must be carefully managed: children should avoid strenuous exercise, hot baths, or rough play for at least two hours after taking their daily dose, as an elevated body temperature and heart rate can increase the risk of a treatment-induced allergic reaction.

Comparison Chart

There are two options to avoid a reaction for those with food allergies. One is to continue to avoid the causative food and carry two autoinjectors of epinephrine. The other is to continue to do those things, as well as daily oral immunotherapy.

This chart explains more about the two options.

Option

Food oral immunotherapy treatment

Avoidance

How does it work?

Precise dosed food is consumed once a day. (It should be taken with food or after eating.)

The child visits the doctor every two weeks for at least the first six months to be given a higher dose of the allergenic food and is observed for 60 minutes for a reaction. During the first visit, the patient may receive one dose, or several increased doses in the allergist’s office for a few hours. Once the daily dose is reached, the patient will take the treatment daily with a meal and follow up with their allergist regularly

The caregiver/child reads labels and avoids ingestion of the allergenic food(s), and carries two epinephrine autoinjectors at all times.

The caregiver/child reads labels and avoids ingestion of the allergenic food(s), and carries two epinephrine autoinjectors at all times.

What are the advantages?

The child is less likely to react to accidental allergenic food exposure.

May help the child feel more comfortable in social situations.

Current standard of care.

No need to take daily treatment and no risk of reaction from that treatment.

No need to adjust activities based on peanut dosing.

What are the possible side effects or limitations?

Most common: Stomach ache and itchy mouth or throat, which likely will decrease over time.

Risk of hives and swelling, congestion and runny nose, wheezing, asthma developing or worsening and anaphylaxis

Risk of anaphylaxis, during buildup and maintenance is higher than avoidance.

Very small risk of eosinophilic esophagitis, an inflammatory reaction of the tube that connects the mouth and stomach.

The child should delay taking the treatment after exercising until they have stopped flushing, sweating and breathing rapidly and no longer have a rapid heart rate. Also, the child should not take a hot bath or shower immediately before the treatment or within three hours afterward.

A lower dose or no dose should be taken if the child has a fever, infection or is feeling ill.

None

What are the possible disadvantages?

Risk of reactions to the therapy including possible anaphylaxis.

Risk of development of eosinophilic esophagitis.

There is a greater risk of allergic reaction due to:

– Exercise

– Hot water exposure

– Fasting

— Menstruation

– Sleep deprivation

– Use of nonsteroidal anti-inflammatory medication (such as Advil® and Aleve®)

– Uncontrolled asthma

Of note, many children and adolescents with peanut allergies do not like the taste of peanuts, making the therapy challenging, especially in younger children.

Must be taken every day indefinitely or it stops working.

 

 

Reactions can occur at lower levels of exposure to the allergenic food.

What is the cost of treatment?

$$$

Includes two epinephrine autoinjectors, the treatment and seeing the allergist every two weeks for at least six months.

Financial assistance may be available – ask your allergist.

Work with your allergist to determine what it will cost based on your insurance.

$

Includes two epinephrine autoinjectors.

What else should I know?

The treatment is not a cure and does not enable the child to eat the allergenic food freely.

The treatment only reduces the risk of reaction to the specific allergenic food, not other food allergens.

The treatment must be refrigerated and taken with a meal.

This treatment is available for any age, but we see better results with younger children.

Most children do not outgrow food allergies.

 

If this treatment is right for you, call and schedule a consultation with any of our providers at 916-453-8696.

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